| Paper | |
|---|---|
| (SPARCL) High-Dose Atorvastatin after Stroke or Transient Ischemic Attack _____ RCT comparing atorvastatin 80 mg to placebo in patients with recent stroke or TIA and LDL 100-190, finding significantly fewer recurrent strokes and major cardiovascular events in the statin group over 5 years, with a small increase in the number of hemorrhagic strokes. | LINK |
| (Treat Stroke to Target) A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke _____ RCT comparing a target LDL <70 to LDL 90-110 using a statin, ezetimibe or both in patients with recent stroke or TIA as well as cerebrovascular or coronary atherosclerotic disease, finding significantly fewer major cardiovascular events in the lower-target group without increased incidence of ICH or newly diagnosed diabetes. | LINK |