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(FLAME) Fluoxetine for motor recovery after acute ischaemic stroke: a randomised placebo-controlled trial _____ A small French RCT comparing fluoxetine to placebo for motor recovery post-stroke, suggesting significant improvement in motor recovery at 3 months in the fluoxetine group | LINK |
(FOCUS) Effects of fluoxetine on functional outcomes after acute stroke: a pragmatic, double-blink, randomised, controlled trial _____ A larger UK RCT comparing fluoxetine to placebo for functional recovery post-stroke, finding no significant difference in 6 month functional status between groups, though fluoxetine use was associated with lower rates of new depression and higher rates of bone fractures | LINK |